Recombinant Mouse Macrophage colony-stimulating factor 1 (Csf1), partial (Active), Mus musculus (Mouse), Mammalian cell, C-terminal 10xHis-tagged, 27.4 kDa, purity >90% as determined by SEC-HPLC.Greater than 95% as determined by SDS-PAGE.
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Recombinant Mouse Macrophage colony-stimulating factor 1 (Csf1), partial (Active)

Recombinant Mouse Macrophage colony-stimulating factor 1 (Csf1), partial (Active) — Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and m… Purity >90%.

SKU: BCACP-000388 Categories: ,
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Product SKUBCACP-000388
Product DescriptionRecombinant Mouse Macrophage colony-stimulating factor 1 (Csf1) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 33-262aa. [Accession | P07141].
Uniprot No.P07141
Gene NamesCsf1
PurityGreater than 90% as determined by SEC-HPLC.Greater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region33-262aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 10xHis-tagged
Molecular weight27.4 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Macaca fascicularis NECTIN2 at 2 μg/mL can bind Anti-NECTIN2 recombinant antibody. The EC50 is 1.011-1.193 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesMacrophage colony-stimulating factor 1; CSF-1; MCSF; Proteoglycan macrophage colony-stimulating factor; Cleaved into 2 chains Processed macrophage colony-stimulating factor 1; Macrophage colony-stimulating factor 1 43 kDa subunit; Csf1; Csfm

Function

Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development.

Product Specifications

Recombinant Mouse Macrophage colony-stimulating factor 1 (Csf1), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 33-262aa, with C-terminal 10xHis-tagged tag, molecular weight 27.4 kDa, purity Greater than 90% as determined by SEC-HPLC.Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Macaca fascicularis NECTIN2 at 2 μg/mL can bind Anti-NECTIN2 recombinant antibody. The EC50 is 1.011-1.193 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance

Gene: Csf1  |  Organism: Mus musculus

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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