Recombinant Mouse Protein S100-A8 (S100a8), Mus musculus (Mouse), E.coli, N-terminal 6xHis-SUMO-tagged, 26.2kDa, purity >90% as determined by SDS-PAGE.

Recombinant Mouse Protein S100-A8 (S100a8)

Recombinant Mouse Protein S100-A8 (S100a8) — recombinant protein from Mus musculus (Mouse), expressed in E.coli. Purity >90%.

SKU: BCRECP-004350 Category:
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Product Specifications

Product SkuBCRECP-004350
Product DescriptionRecombinant Mouse Protein S100-A8 (S100a8) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 2-89aa. [Accession | P27005].
Uniprot No.P27005
Gene NamesS100a8
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region2-89aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight26.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

(Microbial infection) Upon infection by murine coronavirus (MHV-A59), induces expansion of aberrant immature neutrophils in a TLR4-dependent manner.

Biological Context

Subcellular Location: Secreted; Cytoplasm; Cytoplasm, cytoskeleton; Cell membrane (Peripheral membrane protein)

Product Specifications

Recombinant Mouse Protein S100-A8 (S100a8) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 2-89aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 26.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Upon infection by murine coronavirus (MHV-A59), induces expansion of aberrant immature neutrophils in a TLR4-dependent manner

Subcellular Location

Secreted; Cytoplasm; Cytoplasm, cytoskeleton; Cell membrane (Peripheral membrane protein)

Subunit

Homodimer. Preferentially exists as a heterodimer or heterotetramer with S100A9 known as calprotectin (S100A8/A9). Calprotectin (S100A8/9) interacts with CEACAM3 and tubulin filaments in a calcium-dependent manner. Heterotetrameric calprotectin (S100A8/A9) interacts with ANXA6 and associates with tubulin filaments in activated monocytes. S100A8 and calprotectin (S100A8/9) interact with NCF2/P67PHOX, RAC1 and RAC2. Calprotectin (S100A8/9) interacts with CYBA and CYBB (By similarity). S100A8 interacts with AGER, ATP2A2 and with the heterodimeric complex formed by TLR4 and LY96. Calprotectin (S100A8/9) interacts with NOS2 to form the iNOS-S100A8/A9 transnitrosylase complex (By similarity). Calprotectin (S100A8/9) interacts with CD69 (By similarity)

Gene: S100a8  |  Organism: Mus musculus  |  Synonyms: Calgranulin-A; Chemotactic cytokine CP-10; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; Pro-inflammatory S100 cytokine; S100 calcium-binding protein A8
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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