Recombinant Mouse Regenerating islet-derived protein 3-gamma (Reg3g), partial

Recombinant Mouse Regenerating islet-derived protein 3-gamma (Reg3g), partial — Has bactericidal activity against L. Purity >85%.

SKU: BCRECP-004251 Category:

Product Specifications

Product SkuBCRECP-004251
Product DescriptionRecombinant Mouse Regenerating islet-derived protein 3-gamma (Reg3g) Protein is expressed from E.coli with Tag-Free. It contains 27-174aa. [Accession | O09049].
Uniprot No.O09049
Gene NamesReg3g
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region27-174aa
SpeciesMus musculus (Mouse)
Tag InfoTag-Free
Molecular weight16.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus.

Biological Context

Subcellular Location: Secreted; Cytoplasm
Tissue Specificity: Predominantly expressed in the small intestine, including Paneth cells (at protein level). Hardly detectable in the colon (at protein level). Highly expressed in the lung epithelium during methicillin-resistant S.aureus infection and allergic airway inflammation (at protein level). Skin injury increases its epidermal expression. Also expressed in the pancreas. Expressed by nocireceptors

Product Specifications

Recombinant Mouse Regenerating islet-derived protein 3-gamma (Reg3g), partial is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 27-174aa, with Tag-Free tag, molecular weight 16.5kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus

Subcellular Location

Secreted; Cytoplasm

Tissue Specificity

Predominantly expressed in the small intestine, including Paneth cells (at protein level). Hardly detectable in the colon (at protein level) (PubMed:16504538, PubMed:16931762, PubMed:17635956, PubMed:21998396). Highly expressed in the lung epithelium during methicillin-resistant S.aureus infection and allergic airway inflammation (at protein level) (PubMed:28811323). Skin injury increases its epidermal expression (PubMed:22727489, PubMed:23401489, PubMed:27830702). Also expressed in the pancreas (PubMed:9055810). Expressed by nocireceptors (PubMed:35263589)

Subunit

Forms a hexameric membrane-permeabilizing oligomeric pore on membrane phospholipids. The hexamer is formed by three dimers related by helical symmetry. Forms filaments, filamentation traps pore complexes and limits damage to host cells. Interacts with EXTL3

Gene: Reg3g  |  Organism: Mus musculus  |  Synonyms: Pancreatitis-associated protein 3; Regenerating islet-derived protein III-gamma
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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