Recombinant Mouse Sclerostin (Sost), Mus musculus (Mouse), Baculovirus, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 25kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse Sclerostin (Sost)

Recombinant Mouse Sclerostin (Sost) — recombinant protein from Mus musculus (Mouse), expressed in Baculovirus. Purity >85%.

SKU: BCRECP-004451 Category:
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Product Specifications

Product SkuBCRECP-004451
Product DescriptionRecombinant Mouse Sclerostin (Sost) Protein is expressed from Baculovirus with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 24-211aa. [Accession | Q99P68].
Uniprot No.Q99P68
Gene NamesSost
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemBaculovirus
Expression Region24-211aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight25kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Biological Context

Subcellular Location: Secreted, extracellular space, extracellular matrix

Product Specifications

Recombinant Mouse Sclerostin (Sost) is a recombinant protein from Mus musculus (Mouse), expressed in Baculovirus, covering amino acids 24-211aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 25kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation

Subcellular Location

Secreted, extracellular space, extracellular matrix

Subunit

Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6

Gene: Sost  |  Organism: Mus musculus
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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