Function
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone.
Biological Context
Subcellular Location: Cytoplasm; Cytoplasm, perinuclear region; Cell projection, growth cone; Cell projection, axon; Membrane (Peripheral membrane protein); Endosome; Golgi apparatus; Cell projection, lamellipodium
Tissue Specificity: Neuron specific
Product Specifications
Recombinant Mouse Stathmin-2 (Stmn2) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 1-179aa, with C-terminal 6xHis-tagged tag, molecular weight 27.7kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
