Recombinant Mouse Tenascin (Tnc), partial, Mus musculus (Mouse), Mammalian cell, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 28.8kDa, purity >90% as determined by SDS-PAGE.

Recombinant Mouse Tenascin (Tnc), partial

Recombinant Mouse Tenascin (Tnc), partial — Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Purity >90%.

SKU: BCRECP-004583 Category:
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Product Specifications

Product SkuBCRECP-004583
Product DescriptionRecombinant Mouse Tenascin (Tnc) Protein is expressed from Mammalian cell with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 1884-2099aa. [Accession | Q80YX1].
Uniprot No.Q80YX1
Gene NamesTnc
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region1884-2099aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight28.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth when provided to neurons in culture. May play a role in supporting the growth of epithelial tumors.

Biological Context

Subcellular Location: Secreted, extracellular space, extracellular matrix
Tissue Specificity: Highly expressed in the thymus and moderately expressed in the brain

Product Specifications

Recombinant Mouse Tenascin (Tnc), partial is a recombinant protein from Mus musculus (Mouse), expressed in Mammalian cell, covering amino acids 1884-2099aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 28.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth when provided to neurons in culture. May play a role in supporting the growth of epithelial tumors. Ligand for integrins ITGA8:ITGB1, ITGA9:ITGB1, ITGAV:ITGB3 and ITGAV:ITGB6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (By similarity)

Subcellular Location

Secreted, extracellular space, extracellular matrix

Tissue Specificity

Highly expressed in the thymus and moderately expressed in the brain

Subunit

Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4 (By similarity). Interacts (via the 3rd fibronectin type-III domain) with integrin ITGA9:ITGB1 (PubMed:22654117)

Gene: Tnc  |  Organism: Mus musculus  |  Synonyms: Hexabrachion; Tenascin-C
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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