Recombinant Puumala virus Envelope glycoprotein (GP), partial, Puumala virus (strain Berkel), E.coli, C-terminal 6xHis-tagged, 36.3kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Puumala virus Envelope glycoprotein (GP), partial

Recombinant Puumala virus Envelope glycoprotein (GP), partial — Forms homotetramers with glycoprotein N at the surface of the virion. Purity >95%.

SKU: BCRECP-002887 Categories: ,
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Product Specifications

Product SkuBCRECP-002887
Product DescriptionRecombinant Puumala virus Envelope glycoprotein (GP) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 1-275aa. [Accession | P41264].
Uniprot No.P41264
Gene NamesGP
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-275aa
SpeciesPuumala virus (strain Berkel)
Tag InfoC-terminal 6xHis-tagged
Molecular weight36.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Forms homotetramers with glycoprotein N at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis.

Biological Context

Subcellular Location: Virion membrane (Single-pass type I membrane protein); Host cell surface; Host Golgi apparatus membrane (Single-pass type I membrane protein); Host endoplasmic reticulum membrane (Single-pass type I membrane protein)

Product Specifications

Recombinant Puumala virus Envelope glycoprotein (GP), partial is a recombinant protein from Puumala virus (strain Berkel), expressed in E.coli, covering amino acids 1-275aa, with C-terminal 6xHis-tagged tag, molecular weight 36.3kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Forms homotetramers with glycoprotein N at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Class II fusion protein that promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion

Subcellular Location

Virion membrane (Single-pass type I membrane protein); Host cell surface; Host Golgi apparatus membrane (Single-pass type I membrane protein); Host endoplasmic reticulum membrane (Single-pass type I membrane protein)

Subunit

Homodimer. Homotetramer; forms heterotetrameric Gn-Gc spikes in the pre-fusion conformation (By similarity). Homotrimer; forms homotrimer in the post-fusion conformation at acidic pH (By similarity). Interacts (via C-terminus) with the nucleoprotein (By similarity)

Gene: GP  |  Organism: Puumala virus (strain Berkel)  |  Synonyms: M polyprotein

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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