Recombinant Rat Atrial natriuretic peptide receptor 3 (Npr3), partial, Rattus norvegicus (Rat), E.coli, N-terminal 6xHis-SUMO-tagged, 64.9kDa, purity >90% as determined by SDS-PAGE.

Recombinant Rat Atrial natriuretic peptide receptor 3 (Npr3), partial

Recombinant Rat Atrial natriuretic peptide receptor 3 (Npr3), partial — Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. Purity >90%.

SKU: BCRECP-003901 Category:
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Product Specifications

Product SkuBCRECP-003901
Product DescriptionRecombinant Rat Atrial natriuretic peptide receptor 3 (Npr3) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 41-477aa. [Accession | P41740].
Uniprot No.P41740
Gene NamesNpr3
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region41-477aa
SpeciesRattus norvegicus (Rat)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight64.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein)

Product Specifications

Recombinant Rat Atrial natriuretic peptide receptor 3 (Npr3), partial is a recombinant protein from Rattus norvegicus (Rat), expressed in E.coli, covering amino acids 41-477aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 64.9kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production

Subcellular Location

Cell membrane (Single-pass type I membrane protein)

Subunit

Homodimer; disulfide-linked. Interacts with OSTN

Gene: Npr3  |  Organism: Rattus norvegicus  |  Synonyms: Atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide receptor type C

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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