Recombinant Rat Follicle-stimulating hormone receptor (Fshr) Protein, Rattus norvegicus (Rat), in vitro E.coli expression system, C-terminal Twin-Strep-tagged, 79.2kDa, purity >90% as determined by SDS-PAGE.

Recombinant Rat Follicle-stimulating hormone receptor (Fshr) Protein

Recombinant Rat Follicle-stimulating hormone receptor (Fshr) Protein — G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Purity >90%.

SKU: BCRECP-00275TM Category:
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Product Specifications

Uniprot No.P20395
Gene NamesFshr
PurityGreater than 90% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region18-692aa
SpeciesRattus norvegicus (Rat)
Tag InfoC-terminal Twin-Strep-tagged
Molecular weight79.2kDa
ActivityNot Test
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)
Tissue Specificity: Sertoli cells and ovarian granulosa cells

Product Specifications

Recombinant Rat Follicle-stimulating hormone receptor (Fshr) Protein is a recombinant protein from Rattus norvegicus (Rat), expressed in in vitro E.coli expression system, covering amino acids 18-692aa, with C-terminal Twin-Strep-tagged tag, molecular weight 79.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not Test

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Tissue Specificity

Sertoli cells and ovarian granulosa cells

Subunit

Homotrimer. Functions as a homotrimer binding the FSH hormone heterodimer composed of CGA and FSHB (By similarity). Interacts with ARRB2 (PubMed:12850288). Interacts with APPL2; interaction is independent of follicle stimulating hormone stimulation (By similarity)

Gene: Fshr  |  Organism: Rattus norvegicus  |  Synonyms: Follitropin receptor

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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