Recombinant Sheep Fibroblast growth factor 2 (FGF2) (Active), Ovis aries (Sheep), Yeast, C-terminal 6xHis-tagged, 17.9 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Sheep Fibroblast growth factor 2 (FGF2) (Active)

Recombinant Sheep Fibroblast growth factor 2 (FGF2) (Active) — Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Purity >95%.

SKU: BCACP-000345 Categories: ,
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Product SKUBCACP-000345
Product DescriptionRecombinant Sheep Fibroblast growth factor 2 (FGF2) protein is expressed from Yeast with C-terminal 6xHis-tagged. It contains 10-155aa. [Accession | P20003].
Uniprot No.P20003
Gene NamesFGF2
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region10-155aa
SpeciesOvis aries (Sheep)
Tag InfoC-terminal 6xHis-tagged
Molecular weight17.9 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human LTBR at 2 μg/mL can bind Anti-LTBR recombinant antibody , the EC50 is 0.5282-0.6120 ng/mL.;Measured by its binding ability in a functional ELISA. Immobilized Human LTBR at 2 μg/ml can bind human TNFSF14 , the EC50 is 7.283-8.859 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesFibroblast growth factor 2; FGF-2; Basic fibroblast growth factor (bFGF); Heparin-binding growth factor 2 (HBGF-2); FGF2

Function

Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3.

Product Specifications

Recombinant Sheep Fibroblast growth factor 2 (FGF2) (Active) is a recombinant protein, expressed in Yeast, covering amino acids 10-155aa, with C-terminal 6xHis-tagged tag, molecular weight 17.9 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human LTBR at 2 μg/mL can bind Anti-LTBR recombinant antibody , the EC50 is 0.5282-0.6120 ng/mL.;Measured by its binding ability in a functional ELISA. Immobilized Human LTBR at 2 μg/ml can bind human TNFSF14 , the EC50 is 7.283-8.859 ng/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Also acts as an integrin ligand which is required for FGF2 signaling (By similarity). Binds to integrin ITGAV:ITGB3 (By similarity). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity). Functions as a potent mitogen in vitro (By similarity). Can induce angiogenesis (By similarity). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity)

Gene: FGF2  |  Organism: Ovis aries

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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