Recombinant Staphylococcus aureus Clumping factor B(clfB) , partial

Recombinant Staphylococcus aureus Clumping factor B(clfB) , partial — Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps. Purity >85%.

SKU: BCRECP-002391 Category:

Product Specifications

Product SkuBCRECP-002391
Product DescriptionRecombinant Staphylococcus aureus Clumping factor B(clfB) Protein is expressed from Yeast with N-terminal 6xHis-tagged. It contains 45-542aa. [Accession | O86476].
Uniprot No.O86476
Gene NamesclfB
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region45-542aa
SpeciesStaphylococcus aureus (strain Newman)
Tag InfoN-terminal 6xHis-tagged
Molecular weight56.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps. Partly responsible for mediating bacterial attachment to the highly keratinized squamous epithelial cells from the nasal cavity via an interaction with cytokeratin K10 (K10). Also promotes bacterial attachment to cultured keratinocytes, possibly through an interaction with cytokeratin K10.

Biological Context

Subcellular Location: Secreted, cell wall (Peptidoglycan-anchor)

Product Specifications

Recombinant Staphylococcus aureus Clumping factor B(clfB) , partial is a recombinant protein from Staphylococcus aureus (strain Newman), expressed in Yeast, covering amino acids 45-542aa, with N-terminal 6xHis-tagged tag, molecular weight 56.1kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps. Partly responsible for mediating bacterial attachment to the highly keratinized squamous epithelial cells from the nasal cavity via an interaction with cytokeratin K10 (K10). Also promotes bacterial attachment to cultured keratinocytes, possibly through an interaction with cytokeratin K10. Binds mouse cytokeratin K10. Activates human platelet aggregation

Subcellular Location

Secreted, cell wall (Peptidoglycan-anchor)

Gene: clfB  |  Organism: Staphylococcus aureus (strain Newman)  |  Synonyms: Fibrinogen receptor B; Fibrinogen-binding protein B
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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