Recombinant Streptococcus pneumoniae Immunoglobulin A1 protease (iga), partial, Streptococcus pneumoniae, E.coli, C-terminal 6xHis-tagged, 16.1kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Streptococcus pneumoniae Immunoglobulin A1 protease (iga), partial

Recombinant Streptococcus pneumoniae Immunoglobulin A1 protease (iga), partial — Zinc metalloproteinase which cleaves human immunoglobulin A1 (IgA1) in the hinge region, rendering it less efficient in coating the surface of colonizing or invading pneumococci. Purity >90%.

SKU: BCRECP-003086 Categories: , ,
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Product Specifications

Product SkuBCRECP-003086
Product DescriptionRecombinant Streptococcus pneumoniae Immunoglobulin A1 protease (iga) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 313-393aa. [Accession | Q54875].
Uniprot No.Q54875
Gene Namesiga
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region313-393aa
SpeciesStreptococcus pneumoniae
Tag InfoC-terminal 6xHis-tagged
Molecular weight16.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Zinc metalloproteinase which cleaves human immunoglobulin A1 (IgA1) in the hinge region, rendering it less efficient in coating the surface of colonizing or invading pneumococci. May be responsible for pneumococcal infection and is potentially involved in distinct stages of pneumococcal disease.

Biological Context

Subcellular Location: Secreted, cell wall; Membrane (Multi-pass membrane protein); Secreted, cell wall (Peptidoglycan-anchor)

Product Specifications

Recombinant Streptococcus pneumoniae Immunoglobulin A1 protease (iga), partial is a recombinant protein from Streptococcus pneumoniae, expressed in E.coli, covering amino acids 313-393aa, with C-terminal 6xHis-tagged tag, molecular weight 16.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Zinc metalloproteinase which cleaves human immunoglobulin A1 (IgA1) in the hinge region, rendering it less efficient in coating the surface of colonizing or invading pneumococci. May be responsible for pneumococcal infection and is potentially involved in distinct stages of pneumococcal disease

Subcellular Location

Secreted, cell wall; Membrane (Multi-pass membrane protein); Secreted, cell wall (Peptidoglycan-anchor)

Gene: iga  |  Organism: Streptococcus pneumoniae  |  Synonyms: IgA-specific zinc metalloproteinase

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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