Recombinant Mouse Vitamin D-binding protein (Gc), Mus musculus (Mouse), Yeast, N-terminal 6xHis-tagged, 53.9kDa, purity >95% as determined by SDS-PAGE.

Recombinant Mouse Vitamin D-binding protein (Gc)

Recombinant Mouse Vitamin D-binding protein (Gc) — recombinant protein from Mus musculus (Mouse), expressed in Yeast. Purity >95%.

SKU: BCRECP-002832 Category:
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Product Specifications

Product SkuBCRECP-002832
Product DescriptionRecombinant Mouse Vitamin D-binding protein (Gc) Protein is expressed from Yeast with N-terminal 6xHis-tagged. It contains 17-476aa. [Accession | P21614].
Uniprot No.P21614
Gene NamesGc
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region17-476aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-tagged
Molecular weight53.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Mouse Vitamin D-binding protein (Gc) is a recombinant protein from Mus musculus (Mouse), expressed in Yeast, covering amino acids 17-476aa, with N-terminal 6xHis-tagged tag, molecular weight 53.9kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation

Subcellular Location

Secreted

Subunit

Associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes (By similarity). Interacts with LRP2; the interaction is required for renal uptake of GC in complex with 25-hydroxyvitamin D3 (PubMed:10052453)

Gene: Gc  |  Organism: Mus musculus  |  Synonyms: Gc-globulin; Group-specific component
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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