Recombinant Human Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal hFc1-tagged, 40.8 kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), partial (Active)

Recombinant Human Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), partial (Active) — Receptor for TNFSF18. Purity >90%.

SKU: BCACP-000093 Categories: ,
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Product SKUBCACP-000093
Product DescriptionRecombinant Human Tumor necrosis factor receptor superfamily member 18 (TNFRSF18) protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 26-162aa. [Accession | Q9Y5U5].
Uniprot No.Q9Y5U5
Gene NamesTNFRSF18
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region26-162aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight40.8 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized TNFRSF18 at 2 μg/ml can bind TNFSF18 , the EC50 is 2.565 to 2.940 ng/ml.;Human TNFRSF18 protein hFc tag captured on COOH chip can bind Human TNFSF18 protein hFc and Flag tag with an affinity constant of 38.5 nM as detected by LSPR Assay.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative Names(CD357)(AITR)(GITR)

Function

Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed in lymph node, peripheral blood leukocytes and weakly in spleen

Product Specifications

Recombinant Human Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 26-162aa, with C-terminal hFc1-tagged tag, molecular weight 40.8 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway

Subcellular Location

Secreted

Tissue Specificity

Expressed in lymph node, peripheral blood leukocytes and weakly in spleen

Subunit

Binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6. Binds through its C-terminus to SIVA1/SIVA

Gene: TNFRSF18  |  Organism: Homo sapiens  |  Synonyms: Activation-inducible TNFR family receptor; Glucocorticoid-induced TNFR-related protein
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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