Recombinant Human Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) (Active)

SKU: BCACP-000101 Category:
Product SKUBCACP-000101
Product DescriptionRecombinant Human Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) protein is expressed from Mammalian cell with C-terminal hFc1-Flag-tagged. It contains 22-401aa. [Accession | O00300].
Uniprot No.O00300
Gene NamesTNFRSF11B
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region22-401aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-Flag-tagged
Molecular weight73.5 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized NRG1 at 2 μg/ml can bind human ERBB3(CSB-MP007765HU), the EC50 is 18.24-23.66 ng/ml.;The ED50 as determined by the dose-dependent stimulation of the proliferation of MCF-7 cells is 2.626-7.598 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative Names(Osteoclastogenesis inhibitory factor)(Osteoprotegerin)(OCIF)(OPG)

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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