Recombinant Mouse Glucagon-like peptide 1 receptor (Glp1r), partial (Active), Mus musculus (Mouse), Mammalian cell, C-terminal 10xHis-tagged, 15.8 kDa, purity >90% as determined by SDS-PAGE.

Recombinant Mouse Glucagon-like peptide 1 receptor (Glp1r), partial (Active)

Recombinant Mouse Glucagon-like peptide 1 receptor (Glp1r), partial (Active) — G protein-coupled receptor for glucagon-like peptide 1 (GLP-1). Purity >90%.

SKU: BCACP-000364 Category:
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Product SKUBCACP-000364
Product DescriptionRecombinant Mouse Glucagon-like peptide 1 receptor (Glp1r) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 22-145aa. [Accession | O35659].
Uniprot No.O35659
Gene NamesGlp1r
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region22-145aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 10xHis-tagged
Molecular weight15.8 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human FCGR3A at 2 μg/mL can bind Anti-FCGR3A recombinant antibody . The EC50 is 0.2330-0.3147 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesGlucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R;Glp1r

Function

G protein-coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)
Tissue Specificity: Detected in pancreatic islets (at protein level). Detected in pancreatic islets and lungs

Product Specifications

Recombinant Mouse Glucagon-like peptide 1 receptor (Glp1r), partial (Active) is a recombinant protein from Mus musculus (Mouse), expressed in Mammalian cell, covering amino acids 22-145aa, with C-terminal 10xHis-tagged tag, molecular weight 15.8 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

G protein-coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:9568699). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (By similarity). Plays a role in regulating insulin secretion in response to GLP-1 (PubMed:9568699)

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Tissue Specificity

Detected in pancreatic islets (at protein level). Detected in pancreatic islets and lungs

Subunit

May form homodimers and heterodimers with GIPR

Gene: Glp1r  |  Organism: Mus musculus

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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