Recombinant Human Killer cell lectin-like receptor subfamily G member 1 (KLRG1), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 31.5kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Killer cell lectin-like receptor subfamily G member 1 (KLRG1), partial

Recombinant Human Killer cell lectin-like receptor subfamily G member 1 (KLRG1), partial — Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. Purity >90%.

SKU: BCRECP-001021 Category:
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Product Specifications

Product SkuBCRECP-001021
Product DescriptionRecombinant Human Killer cell lectin-like receptor subfamily G member 1 (KLRG1) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 60-195aa. [Accession | Q96E93].
Uniprot No.Q96E93
Gene NamesKLRG1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region60-195aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight31.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.

Biological Context

Subcellular Location: Cell membrane (Single-pass type II membrane protein)
Tissue Specificity: Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells

Product Specifications

Recombinant Human Killer cell lectin-like receptor subfamily G member 1 (KLRG1), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 60-195aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 31.5kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells

Subcellular Location

Cell membrane (Single-pass type II membrane protein)

Tissue Specificity

Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells

Subunit

Forms a monomer and homodimer; disulfide-linked. Interacts (via ITIM motif) with PTPN11 and INPP5D

Gene: KLRG1  |  Organism: Homo sapiens  |  Synonyms: C-type lectin domain family 15 member A; ITIM-containing receptor MAFA-L; MAFA-like receptor; Mast cell function-associated antigen
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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