Function
Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
Biological Context
Subcellular Location: Secreted
Disease Association: Keutel syndrome (KTLS) : An autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia. [The disease is caused by variants affecting the gene represented in this entry]
Product Specifications
Recombinant Human Matrix Gla protein (MGP) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 20-96aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 14.5kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
