Recombinant Human Oxidized low-density lipoprotein receptor 1 (OLR1), partial — (Microbial infection) May serve as a receptor for adhesin A variant 3 (nadA) of N. Purity >90%.
| Product Sku | BCRECP-001300 |
| Product Description | Recombinant Human Oxidized low-density lipoprotein receptor 1 (OLR1) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 58-273aa. [Accession | P78380]. |
| Uniprot No. | P78380 |
| Gene Names | OLR1 |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Expression System | E.coli |
| Expression Region | 58-273aa |
| Species | Homo sapiens (Human) |
| Tag Info | N-terminal 6xHis-tagged |
| Molecular weight | 28.7kDa |
| Activity | Please contact us to obtain bioactivity data. |
| Buffer | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose. |
| Storage | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| Research Areas | Cardiovascular |
(Microbial infection) May serve as a receptor for adhesin A variant 3 (nadA) of N.meningitidis.
Recombinant Human Oxidized low-density lipoprotein receptor 1 (OLR1), partial — (Microbial infection) May serve as a receptor for adhesin A variant 3 (nadA) of N. Purity >90%. Suitable for ELISA and Western Blot applications.
SDS-PAGE: Single band at expected molecular weight confirming purity.
ELISA: Suitable as coating antigen or detection standard.
Western Blot: Compatible with standard Western Blot protocols.
Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.
Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.
Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.
Shelf Life: 12 months from date of receipt when stored as recommended.
Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.
(Microbial infection) May serve as a receptor for adhesin A variant 3 (nadA) of N.meningitidis
Cell membrane (Lipid-anchor); Cell membrane (Single-pass type II membrane protein); Membrane raft; Secreted
[Independent association genetic studies have implicated OLR1 gene variants in myocardial infarction susceptibility] | [OLR1 may be involved in Alzheimer disease (AD). Involvement in AD is however unclear: according to some authors, variations in OLR1 modify the risk of AD (PubMed:12354387, PubMed:12810610, PubMed:15976314). While according to others they do not (PubMed:15000751, PubMed:15060104)]
Expressed at high level in endothelial cells and vascular-rich organs such as placenta, lung, liver and brain, aortic intima, bone marrow, spinal cord and substantia nigra. Also expressed at the surface of dendritic cells. Widely expressed at intermediate and low level
(Microbial infection) Binds to the head and beginning of the coiled stalk of N.meningitidis adhesin A (nadA) variant 3; binding can be abrogated by monoclonal antibodies against the specific regions of NadA. Binding occurs in protein microarrays, in solution and when LOX-1 is expressed on the cell surface
Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.
Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.
Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.
Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.
