Recombinant Human Serine/arginine repetitive matrix protein 2 (SRRM2), partial, Homo sapiens (Human), Baculovirus, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 53.8kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Serine/arginine repetitive matrix protein 2 (SRRM2), partial

Recombinant Human Serine/arginine repetitive matrix protein 2 (SRRM2), partial — Required for pre-mRNA splicing as component of the spliceosome. Purity >85%.

SKU: BCRECP-001696 Category:
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Product Specifications

Product SkuBCRECP-001696
Product DescriptionRecombinant Human Serine/arginine repetitive matrix protein 2 (SRRM2) Protein is expressed from Baculovirus with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 1666-2089aa. [Accession | Q9UQ35].
Uniprot No.Q9UQ35
Gene NamesSRRM2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemBaculovirus
Expression Region1666-2089aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight53.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Required for pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).

Biological Context

Subcellular Location: Nucleus; Nucleus speckle
Tissue Specificity: Expressed in liver, placenta, and white blood cells
Disease Association: Intellectual developmental disorder, autosomal dominant 72 (MRD72) : An autosomal dominant disorder characterized by mild developmental delay and intellectual disability, predominant speech delay, autistic or attention deficit-hyperactivity disorder features, overfriendliness, generalized hypotonia, overweight, and dysmorphic facial features. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Serine/arginine repetitive matrix protein 2 (SRRM2), partial is a recombinant protein from Homo sapiens (Human), expressed in Baculovirus, covering amino acids 1666-2089aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 53.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Required for pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable)

Subcellular Location

Nucleus; Nucleus speckle

Disease Association

Intellectual developmental disorder, autosomal dominant 72 (MRD72) : An autosomal dominant disorder characterized by mild developmental delay and intellectual disability, predominant speech delay, autistic or attention deficit-hyperactivity disorder features, overfriendliness, generalized hypotonia, overweight, and dysmorphic facial features. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Expressed in liver, placenta, and white blood cells

Subunit

Component of pre-catalytic, catalytic and post-catalytic spliceosome complexes (PubMed:11991638, PubMed:28076346, PubMed:28502770, PubMed:29301961, PubMed:29360106, PubMed:29361316, PubMed:30705154). Found in a pre-mRNA splicing complex with SFRS4, SFRS5, SNRP70, SNRPA1, SRRM1 and SRRM2 (PubMed:9531537). Component of the minor spliceosome, which splices U12-type introns (PubMed:33509932). Interacts with DHX8 (PubMed:28062851). Interacts with CACTIN (PubMed:28062851)

Gene: SRRM2  |  Organism: Homo sapiens  |  Synonyms: 300 kDa nuclear matrix antigen; Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa; Splicing coactivator subunit SRm300; Tax-responsive enhancer element-binding protein 803
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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