Recombinant Human E3 ubiquitin-protein ligase TRIM9 (TRIM9), Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 77.3kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human E3 ubiquitin-protein ligase TRIM9 (TRIM9)

Recombinant Human E3 ubiquitin-protein ligase TRIM9 (TRIM9) — E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. Purity >90%.

SKU: BCRECP-001855 Categories: ,
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Product Specifications

Product SkuBCRECP-001855
Product DescriptionRecombinant Human E3 ubiquitin-protein ligase TRIM9 (TRIM9) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 1-550aa. [Accession | Q9C026].
Uniprot No.Q9C026
Gene NamesTRIM9
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-550aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight77.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.

Biological Context

Subcellular Location: Cytoplasm; Cell projection, dendrite; Cytoplasmic vesicle, secretory vesicle, synaptic vesicle; Synapse; Cytoplasm, cytoskeleton
Tissue Specificity: Brain. Highly expressed in the cerebral cortex (at protein level). Severely decreased in the affected brain areas in Parkinson disease and dementia with Lewy bodies
Pathway: Protein modification; protein ubiquitination

Product Specifications

Recombinant Human E3 ubiquitin-protein ligase TRIM9 (TRIM9) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-550aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 77.3kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation

Subcellular Location

Cytoplasm; Cell projection, dendrite; Cytoplasmic vesicle, secretory vesicle, synaptic vesicle; Synapse; Cytoplasm, cytoskeleton

Tissue Specificity

Brain. Highly expressed in the cerebral cortex (at protein level). Severely decreased in the affected brain areas in Parkinson disease and dementia with Lewy bodies

Subunit

Interacts with SNAP25

Pathway

Protein modification; protein ubiquitination

Gene: TRIM9  |  Organism: Homo sapiens  |  Synonyms: RING finger protein 91; RING-type E3 ubiquitin transferase TRIM9; Tripartite motif-containing protein 9
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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