Recombinant Bothrops atrox Disintegrin batroxostatin, Bothrops atrox (Barba amarilla) (Fer-de-lance), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 15.2kDa, purity >90% as determined by SDS-PAGE.

Recombinant Bothrops atrox Disintegrin batroxostatin

Recombinant Bothrops atrox Disintegrin batroxostatin — Inhibits fibrinogen interaction with platelets. Purity >90%.

SKU: BCRECP-003612 Category:
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Product Specifications

Product SkuBCRECP-003612
Product DescriptionRecombinant Bothrops atrox Disintegrin batroxostatin Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 1-72aa. [Accession | P18618].
Uniprot No.P18618
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-72aa
SpeciesBothrops atrox (Barba amarilla) (Fer-de-lance)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight15.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Also inhibits T24 and SK-Mel-28 cell adhesion to fibronectin with IC(50) of 4.4 uM and 33 nM, respectively.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed by the venom gland

Product Specifications

Recombinant Bothrops atrox Disintegrin batroxostatin is a recombinant protein from Bothrops atrox (Barba amarilla) (Fer-de-lance), expressed in E.coli, covering amino acids 1-72aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 15.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Also inhibits T24 and SK-Mel-28 cell adhesion to fibronectin with IC(50) of 4.4 uM and 33 nM, respectively

Subcellular Location

Secreted

Tissue Specificity

Expressed by the venom gland

Subunit

Monomer

Organism: Bothrops atrox  |  Synonyms: Disintegrin colombistatin; Platelet aggregation activation inhibitor

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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