Recombinant Guinea pig Cytotoxic T-lymphocyte associated protein 4 (CTLA4), partial (Active), Cavia porcellus (Guinea pig), Yeast, C-terminal 6xHis-tagged, 14.1 kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Guinea pig Cytotoxic T-lymphocyte associated protein 4 (CTLA4), partial (Active)

Recombinant Guinea pig Cytotoxic T-lymphocyte associated protein 4 (CTLA4), partial (Active) — Inhibitory receptor acting as a major negative regulator of T-cell responses. Purity >90%.

SKU: BCACP-001267 Categories: ,
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Product SKUBCACP-001267
Product DescriptionRecombinant Guinea pig Cytotoxic T-lymphocyte associated protein 4 (CTLA4) protein is expressed from Yeast with C-terminal 6xHis-tagged. It contains 37-161aa. [Accession | H0VUB1].
Uniprot No.H0VUB1
Gene NamesCTLA4
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region37-161aa
SpeciesCavia porcellus (Guinea pig)
Tag InfoC-terminal 6xHis-tagged
Molecular weight14.1 kDa
ActivityThe ED50 as determined by its ability to bind Human TNFSF5 in functional ELISA is less than 100 ug/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.

Product Specifications

Recombinant Guinea pig Cytotoxic T-lymphocyte associated protein 4 (CTLA4), partial (Active) is a recombinant protein, expressed in Yeast, covering amino acids 37-161aa, with C-terminal 6xHis-tagged tag, molecular weight 14.1 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: The ED50 as determined by its ability to bind Human TNFSF5 in functional ELISA is less than 100 ug/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28

Gene: CTLA4  |  Organism: Cavia porcellus

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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