Recombinant Human Alpha-2-HS-glycoprotein (AHSG), partial (Active), Homo sapiens (Human), Mammalian cell, Tag free, 32.9 kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Alpha-2-HS-glycoprotein (AHSG), partial (Active)

Recombinant Human Alpha-2-HS-glycoprotein (AHSG), partial (Active) — Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Purity >95%.

SKU: BCACP-001121 Category:
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Product SKUBCACP-001121
Product DescriptionRecombinant Human Alpha-2-HS-glycoprotein (AHSG) protein is expressed from Mammalian cell with Tag free. It contains 19-300aa&341-367aa. [Accession | P02765].
Uniprot No.P02765
Gene NamesFetuin A
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region19-300aa&341-367aa
SpeciesHomo sapiens (Human)
Tag InfoTag free
Molecular weight32.9 kDa
ActivityMeasured in a cell proliferation assay using Mv.1.Lu Mink lung epithelial cells. The ED50 for this effect is ≤10 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesAlpha-2-HS-Glycoprotein; Alpha-2-Z-Globulin; Ba-Alpha-2-Glycoprotein; Fetuin-A; AHSG; FETUA

Function

Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins
Disease Association: Alopecia-intellectual disability syndrome 1 (APMR1) : A rare autosomal recessive form of alopecia. APMR1 patients show loss of hair on the scalp, absence of eyebrows, eyelashes, axillary and pubic hair, and mild to severe intellectual disability. [The disease may be caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Alpha-2-HS-glycoprotein (AHSG), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 19-300aa&341-367aa, with Tag free tag, molecular weight 32.9 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions

Subcellular Location

Secreted

Disease Association

Alopecia-intellectual disability syndrome 1 (APMR1) : A rare autosomal recessive form of alopecia. APMR1 patients show loss of hair on the scalp, absence of eyebrows, eyelashes, axillary and pubic hair, and mild to severe intellectual disability. [The disease may be caused by variants affecting the gene represented in this entry]

Tissue Specificity

Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins

Subunit

Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond

Gene: AHSG  |  Organism: Homo sapiens  |  Synonyms: Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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