Recombinant Human Apelin receptor (APLNR)-VLPs (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 44.1 kDa, purity >/
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Recombinant Human Apelin receptor (APLNR)-VLPs (Active)

Recombinant Human Apelin receptor (APLNR)-VLPs (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity /.

SKU: BCACP-000604 Categories: ,
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Product SKUBCACP-000604
Product DescriptionRecombinant Human Apelin receptor (APLNR)-VLPs protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 1-380aa. [Accession | P35414].
Uniprot No.P35414
Gene NamesAPLNR
Purity/
Expression SystemMammalian cell
Expression Region1-380aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight44.1 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human APCS at 2 μg/mL can bind Anti-APCS recombinant antibody . The EC50 is 27.44-31.04 ng/mL.;APCS Recombinant Monoclonal Antibody captured on Protein A Chip can bind Human APCS with an affinity constant of 0.308 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesApelin receptor; Angiotensin receptor-like 1; G-protein coupled receptor APJ; G-protein coupled receptor HG11

Function

(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Biological Context

Subcellular Location: Cell membrane
Tissue Specificity: Expressed in heart, brain, kidney, stomach, spleen, thymus, lung, ovary, small intestine and colon, adipose tissues and pancreas. Expressed in glial cells, astrocytes and neuronal subpopulations. Expressed in embryonic (ESCs) and induced (iPSCs) pluripotent stem cells

Product Specifications

Recombinant Human Apelin receptor (APLNR)-VLPs (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 1-380aa, with C-terminal 10xHis-tagged tag, molecular weight 44.1 kDa, purity /. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human APCS at 2 μg/mL can bind Anti-APCS recombinant antibody . The EC50 is 27.44-31.04 ng/mL.;APCS Recombinant Monoclonal Antibody captured on Protein A Chip can bind Human APCS with an affinity constant of 0.308 nM as detected by MetaSPR Assay (WeSPRTM 200).

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia (PubMed:11090199)

Subcellular Location

Cell membrane

Tissue Specificity

Expressed in heart, brain, kidney, stomach, spleen, thymus, lung, ovary, small intestine and colon, adipose tissues and pancreas (PubMed:25639753, PubMed:8294032). Expressed in glial cells, astrocytes and neuronal subpopulations (PubMed:8294032). Expressed in embryonic (ESCs) and induced (iPSCs) pluripotent stem cells (PubMed:25639753)

Subunit

Homodimer; dimerization inhibits APLNR-mediated G protein and beta-arrestin signaling pathways compared to monomeric APLNR

Gene: APLNR  |  Organism: Homo sapiens  |  Synonyms: Angiotensin receptor-like 1; G protein-coupled receptor APJ; G protein-coupled receptor HG11
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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