Recombinant Macaca mulatta Apelin receptor (APLNR)-VLPs (Active), Macaca mulatta (Rhesus macaque), Mammalian cell, C-terminal 10xHis-tagged, 44.1 kDa, purity >95% as determined by SEC-HPLC.
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Recombinant Macaca mulatta Apelin receptor (APLNR)-VLPs (Active)

Recombinant Macaca mulatta Apelin receptor (APLNR)-VLPs (Active) — recombinant protein from Macaca mulatta (Rhesus macaque), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-000605 Categories: ,
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Product SKUBCACP-000605
Product DescriptionRecombinant Rhesus macaque Apelin receptor (APLNR)-VLPs protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 1-380aa. [Accession | O97666].
Uniprot No.O97666
Gene NamesAPLNR
PurityGreater than 95% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region1-380aa
SpeciesMacaca mulatta (Rhesus macaque)
Tag InfoC-terminal 10xHis-tagged
Molecular weight44.1 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis IL2RA at 2 μg/mL can bind Macaca fascicularis IL2 . The EC50 is 88.60-116.8 ng/mL.;Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis IL2RA at 2 μg/mL can bind Human IL2 . The EC50 is 0.8151-1.087 ng/mL.;Macaca fascicularis IL2 captured on Protein A Chip can bind Recombinant Macaca fascicularis IL2RA with an affinity constant of 31.3 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesApelin receptor; Angiotensin receptor-like 1; G-protein coupled receptor APJ

Function

(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)

Product Specifications

Recombinant Macaca mulatta Apelin receptor (APLNR)-VLPs (Active) is a recombinant protein from Macaca mulatta (Rhesus macaque), expressed in Mammalian cell, covering amino acids 1-380aa, with C-terminal 10xHis-tagged tag, molecular weight 44.1 kDa, purity Greater than 95% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis IL2RA at 2 μg/mL can bind Macaca fascicularis IL2 . The EC50 is 88.60-116.8 ng/mL.;Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis IL2RA at 2 μg/mL can bind Human IL2 . The EC50 is 0.8151-1.087 ng/mL.;Macaca fascicularis IL2 captured on Protein A Chip can bind Recombinant Macaca fascicularis IL2RA with an affinity constant of 31.3 nM as detected by MetaSPR Assay (WeSPRTM 200).

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Subunit

Homodimer; dimerization inhibits APLNR-mediated G protein and beta-arrestin signaling pathways compared to monomeric APLNR

Gene: APLNR  |  Organism: Macaca mulatta  |  Synonyms: Angiotensin receptor-like 1; G protein-coupled receptor APJ

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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