Recombinant Mouse Claudin-18.2 (Cldn18.2)-VLPs (Active), Mus musculus (Mouse), Mammalian cell, N-terminal 6xHis-tagged (This tag can be tested only under denaturing conditions), 29.1 kDa
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Recombinant Mouse Claudin-18.2 (Cldn18.2)-VLPs (Active)

Recombinant Mouse Claudin-18.2 (Cldn18.2)-VLPs (Active) — recombinant protein, expressed in Mammalian cell.

SKU: BCACP-000197 Categories: ,
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Product SKUBCACP-000197
Product DescriptionRecombinant Mouse Claudin-18.2 (Cldn18.2)-VLPs protein is expressed from Mammalian cell with N-terminal 6xHis-tagged (This tag can be tested only under denaturing conditions). It contains 1-264aa. [Accession | P56857-3].
Uniprot No.P56857-3
Gene NamesCldn18.2
Expression SystemMammalian cell
Expression Region1-264aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-tagged (This tag can be tested only under denaturing conditions)
Molecular weight29.1 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human CLDN4 at 5 μg/mL can bind Anti-CLDN4 recombinant antibody , the EC50 is 29.56-50.75 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Required for the formation of the gastric paracellular barrier via its role in tight junction formation, thereby involved in the response to gastric acidification.

Product Specifications

Recombinant Mouse Claudin-18.2 (Cldn18.2)-VLPs (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 1-264aa, with N-terminal 6xHis-tagged (This tag can be tested only under denaturing conditions) tag, molecular weight 29.1 kDa. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Required for the formation of the gastric paracellular barrier via its role in tight junction formation, thereby involved in the response to gastric acidification

Gene: Cldn18  |  Organism: Mus musculus

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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