Recombinant Human IL12P40&P19 Heterodimer Protein (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.
| Product SKU | BCACP-001146 |
| Product Description | Recombinant Human IL12P40&P19 Heterodimer Protein protein is expressed from Mammalian cell with Tag free. It contains 23-328aa(IL12P40)&20-189aa(P19). [Accession | P29460 AAG37232]. |
| Uniprot No. | P29460 AAG37232 |
| Gene Names | IL-23 |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| Expression System | Mammalian cell |
| Expression Region | 23-328aa(IL12P40)&20-189aa(P19) |
| Species | Homo sapiens (Human) |
| Tag Info | Tag free |
| Molecular weight | 55.0 kDa (IL-23 single chain); 36.5 kDa (p40) & 18.5 kDa (p19) |
| Activity | Determined by its ability to inhibit 5.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 2.0-3.0 ng/ml of Noggin. |
| Buffer | Lyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0 |
| Storage | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| Alternative Names | SGRF; IL-23p19; CLMF p40; IL-12 subunit p40; NKSF2 |
Recombinant Human IL12P40&P19 Heterodimer Protein (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 23-328aa(IL12P40)&20-189aa(P19), with Tag free tag, molecular weight 55.0 kDa (IL-23 single chain); 36.5 kDa (p40) & 18.5 kDa (p19), purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Determined by its ability to inhibit 5.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 2.0-3.0 ng/ml of Noggin.
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.
Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.
Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.
Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.
