Recombinant Human Interleukin-17 receptor A (IL17RA), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal hFc-tagged, 60.6 kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Interleukin-17 receptor A (IL17RA), partial (Active)

Recombinant Human Interleukin-17 receptor A (IL17RA), partial (Active) — recombinant protein, expressed in Mammalian cell. Purity >90%.

SKU: BCACP-001008 Categories: ,
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Product SKUBCACP-001008
Product DescriptionRecombinant Human Interleukin-17 receptor A (IL17RA) protein is expressed from Mammalian cell with C-terminal hFc-tagged. It contains 33-320aa. [Accession | Q96F46].
Uniprot No.Q96F46
Gene NamesIL17RA
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region33-320aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc-tagged
Molecular weight60.6 kDa
ActivityThe ED50 as determined by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells is 1-10 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesCANDF5; CD217; CD217 antigen; CDw217; CTLA8; HIL 17R; hIL17R; I17RA_HUMAN; IL 17 receptor A; IL 17 receptor; IL 17RA; IL-17 receptor A; IL-17RA; IL17; IL17A receptor; IL17R; IL17RA; IMD51; Interleukin 17 receptor A; Interleukin-17 receptor A; MGC10262

Function

(Microbial infection) Receptor for SARS coronavirus-2/SARS-CoV-2 virus protein ORF8, leading to IL17 pathway activation and an increased secretion of pro-inflammatory factors through activating NF-kappa-B signaling pathway.

Product Specifications

Recombinant Human Interleukin-17 receptor A (IL17RA), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 33-320aa, with C-terminal hFc-tagged tag, molecular weight 60.6 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: The ED50 as determined by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells is 1-10 ng/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Receptor for SARS coronavirus-2/SARS-CoV-2 virus protein ORF8, leading to IL17 pathway activation and an increased secretion of pro-inflammatory factors through activating NF-kappa-B signaling pathway

Gene: IL17RA  |  Organism: Homo sapiens

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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