Recombinant Human Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 25.9 kDa, purity >95% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.

Recombinant Human Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3), partial (Active)

Recombinant Human Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3), partial (Active) — Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Purity >95%.

SKU: BCACP-000642 Category:
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Product SKUBCACP-000642
Product DescriptionRecombinant Human Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 22-245aa. [Accession | P43628].
Uniprot No.P43628
Gene NamesKIR2DL3
PurityGreater than 95% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region22-245aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight25.9 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human HAVCR1 at 2 μg/mL can bind Anti-HAVCR1 recombinant antibody . The EC50 is 3.952-4.750 ng/mL.;HAVCR1 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Recombinant Human HAVCR1 with an affinity constant of 0.245 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesKiller cell immunoglobulin-like receptor 2DL3; CD158 antigen-like family member B2; KIR-023GB; Killer inhibitory receptor cl 2-3; NKAT2a; NKAT2b; Natural killer-associated transcript 2; NKAT-2; p58 natural killer cell receptor clone CL-6; p58 NK receptor CL-6; p58.2 MHC class-I-specific NK receptor; CD antigen CD158b2

Function

Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein)

Product Specifications

Recombinant Human Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 22-245aa, with C-terminal 10xHis-tagged tag, molecular weight 25.9 kDa, purity Greater than 95% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human HAVCR1 at 2 μg/mL can bind Anti-HAVCR1 recombinant antibody . The EC50 is 3.952-4.750 ng/mL.;HAVCR1 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Recombinant Human HAVCR1 with an affinity constant of 0.245 nM as detected by MetaSPR Assay (WeSPRTM 200).

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis

Subcellular Location

Cell membrane (Single-pass type I membrane protein)

Subunit

Interacts with ARRB2

Gene: KIR2DL3  |  Organism: Homo sapiens  |  Synonyms: CD158 antigen-like family member B2; KIR-023GB; Killer inhibitory receptor cl 2-3; NKAT2a; NKAT2b; Natural killer-associated transcript 2; p58 natural killer cell receptor clone CL-6; p58.2 MHC class-I-specific NK receptor
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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