Recombinant Human Tetranectin (CLEC3B)

Recombinant Human Tetranectin (CLEC3B) — Tetranectin binds to plasminogen and to isolated kringle 4. Purity >90%.

SKU: BCRECP-000378 Category:

Product Specifications

Product SkuBCRECP-000378
Product DescriptionRecombinant Human Tetranectin (CLEC3B) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 22-202aa. [Accession | P05452].
Uniprot No.P05452
Gene NamesCLEC3B
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region22-202aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight26.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis. Plays a role in retinal function.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Found in plasma
Disease Association: Macular dystrophy, retinal, 4 (MCDR4) : An autosomal dominant retinal disease characterized by late-onset macular degeneration, with multiple drusen-like deposits, macular geographic atrophy, and choroidal neovascularization. Patients also exhibit extensive retinal dysfunction with impaired rod function. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Tetranectin (CLEC3B) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 22-202aa, with N-terminal 6xHis-tagged tag, molecular weight 26.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis. Plays a role in retinal function (PubMed:35331648)

Subcellular Location

Secreted

Disease Association

Macular dystrophy, retinal, 4 (MCDR4) : An autosomal dominant retinal disease characterized by late-onset macular degeneration, with multiple drusen-like deposits, macular geographic atrophy, and choroidal neovascularization. Patients also exhibit extensive retinal dysfunction with impaired rod function. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Found in plasma

Subunit

Homotrimer

Gene: CLEC3B  |  Organism: Homo sapiens  |  Synonyms: C-type lectin domain family 3 member B; Plasminogen kringle 4-binding protein
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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