Recombinant Human Tumor necrosis factor receptor superfamily member 17 protein (TNFRSF17), partial (Active) — Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Purity >98%.
| Product SKU | BCACP-000963 |
| Product Description | Recombinant Human Tumor necrosis factor receptor superfamily member 17 protein (TNFRSF17) protein is expressed from E.Coli with Tag-Free. It contains 5-54aa. [Accession | Q02223]. |
| Uniprot No. | Q02223 |
| Gene Names | TNFRSF17 |
| Purity | >98% as determined by SDS-PAGE. |
| Expression System | E.Coli |
| Expression Region | 5-54aa |
| Species | Homo sapiens (Human) |
| Tag Info | Tag-Free |
| Molecular weight | 5.4 kDa |
| Activity | Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit the cytotoxicity of Jurkat cells is between 10-15 ug/ml in the presence of 2 ng/ml of rHuFas Ligand. |
| Buffer | Lyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0 |
| Storage | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| Alternative Names | B cell maturation antigen; B cell maturation factor; B cell maturation protein; B-cell maturation protein; BCM; BCMA; CD269; CD269 antigen; TNFRSF17; TNR17_HUMAN; Tumor necrosis factor receptor superfamily member 17 |
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity.
Recombinant Human Tumor necrosis factor receptor superfamily member 17 protein (TNFRSF17), partial (Active) — Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Purity >98%. Suitable for ELISA and Western Blot applications. Explore more TNF Family proteins →
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit the cytotoxicity of Jurkat cells is between 10-15 ug/ml in the presence of 2 ng/ml of rHuFas Ligand.
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK
Cell membrane (Single-pass type III membrane protein); Endomembrane system (Single-pass type III membrane protein)
[A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2]
Expressed in mature B-cells, but not in T-cells or monocytes
Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6
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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.
Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.
Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.
Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.
