Function
(Microbial infection) Receptor for C.botulinum neurotoxin type G (BoNT/G, botG); unlike the case with BoNT/B interaction is not improved in the presence of gangliosides. The toxin binds to the vesicular domain of Syt2 (residues 1-61).
Biological Context
Subcellular Location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane (Single-pass membrane protein); Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane (Single-pass membrane protein); Cytoplasm
Tissue Specificity: Predominantly expressed in brain regions such as the spinal cord, brain stem and cerebellum
Product Specifications
Recombinant Rat Synaptotagmin-2 (Syt2) Protein is a recombinant protein from Rattus norvegicus (Rat), expressed in in vitro E.coli expression system, covering amino acids 1-422aa, with N-terminal 10xHis-tagged tag, molecular weight 48.7kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
