Function
Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Biological Context
Subcellular Location: Secreted
Tissue Specificity: Expressed in activated CD8(+) T cells. In the thymus, expressed by medullary thymic epithelial cells
Product Specifications
Recombinant Mouse Lymphotactin protein (Xcl1) (Active) is a recombinant protein from Mus musculus (Mouse), expressed in E.Coli, covering amino acids 22-114aa, with Tag-Free tag, molecular weight 10.1 kDa, purity >97% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
