Recombinant Human Fibroblast growth factor 10 (FGF10) (Active), Homo sapiens (Human), Mammalian cell, Tag free, 19.3 kDa, purity >95% as determined by SDS-PAGE.
,

Recombinant Human Fibroblast growth factor 10 (FGF10) (Active)

Recombinant Human Fibroblast growth factor 10 (FGF10) (Active) — Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Purity >95%.

SKU: BCACP-001126 Categories: ,
Online Inquiry →
Product SKUBCACP-001126
Product DescriptionRecombinant Human Fibroblast growth factor 10 (FGF10) protein is expressed from Mammalian cell with Tag free. It contains 38-208aa. [Accession | O15520].
Uniprot No.O15520
Gene NamesFGF-10/KGF2
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region38-208aa
SpeciesHomo sapiens (Human)
Tag InfoTag free
Molecular weight19.3 kDa
ActivityDetermined by its ability to stimulate the proliferation of Nb2-11 cells. Expected ED50 ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10 7 units/mg
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesFibroblast growth factor 10;FGF-10;Keratinocyte growth factor 2;FGF10;KGF-2;KGF2

Function

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing.

Biological Context

Subcellular Location: Secreted
Disease Association: Aplasia of lacrimal and salivary glands (ALSG) : A rare condition characterized by dry conjunctival mucosae, irritable eyes, epiphora (constant tearing), and xerostomia (dryness of the mouth), which increases risk of dental erosion, dental caries, periodontal disease, and oral infections. ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular, and sublingual glands and absence of the lacrimal puncta. [The disease is caused by variants affecting the gene represented in this entry] | Lacrimo-auriculo-dento-digital syndrome 3 (LADD3) : A form of lacrimo-auriculo-dento-digital syndrome, an autosomal dominant disease characterized by aplastic/hypoplastic lacrimal and salivary glands and ducts, cup-shaped ears, hearing loss, hypodontia and enamel hypoplasia, and distal limb segments anomalies. In addition to these cardinal features, facial dysmorphism, malformations of the kidney and respiratory system and abnormal genitalia have been reported. Craniosynostosis and severe syndactyly are not observed. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Fibroblast growth factor 10 (FGF10) (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 38-208aa, with Tag free tag, molecular weight 19.3 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Determined by its ability to stimulate the proliferation of Nb2-11 cells. Expected ED50 ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10 7 units/mg

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing

Subcellular Location

Secreted

Disease Association

Aplasia of lacrimal and salivary glands (ALSG) : A rare condition characterized by dry conjunctival mucosae, irritable eyes, epiphora (constant tearing), and xerostomia (dryness of the mouth), which increases risk of dental erosion, dental caries, periodontal disease, and oral infections. ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular, and sublingual glands and absence of the lacrimal puncta. [The disease is caused by variants affecting the gene represented in this entry] | Lacrimo-auriculo-dento-digital syndrome 3 (LADD3) : A form of lacrimo-auriculo-dento-digital syndrome, an autosomal dominant disease characterized by aplastic/hypoplastic lacrimal and salivary glands and ducts, cup-shaped ears, hearing loss, hypodontia and enamel hypoplasia, and distal limb segments anomalies. In addition to these cardinal features, facial dysmorphism, malformations of the kidney and respiratory system and abnormal genitalia have been reported. Craniosynostosis and severe syndactyly are not observed. [The disease is caused by variants affecting the gene represented in this entry]

Subunit

Interacts with FGFR1 and FGFR2. Interacts with FGFBP1

Gene: FGF10  |  Organism: Homo sapiens  |  Synonyms: Keratinocyte growth factor 2

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top