Recombinant Human Fibroblast growth factor 10 (FGF10) (Active), Homo sapiens (Human), Mammalian cell, Tag free, 19.3 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human Fibroblast growth factor 10 (FGF10) (Active)

Recombinant Human Fibroblast growth factor 10 (FGF10) (Active) — Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Purity >95%.

SKU: BCACP-001126 Categories: ,
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Product SKUBCACP-001126
Product DescriptionRecombinant Human Fibroblast growth factor 10 (FGF10) protein is expressed from Mammalian cell with Tag free. It contains 38-208aa. [Accession | O15520].
Uniprot No.O15520
Gene NamesFGF-10/KGF2
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region38-208aa
SpeciesHomo sapiens (Human)
Tag InfoTag free
Molecular weight19.3 kDa
ActivityDetermined by its ability to stimulate the proliferation of Nb2-11 cells. Expected ED50 ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10 7 units/mg
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesFibroblast growth factor 10;FGF-10;Keratinocyte growth factor 2;FGF10;KGF-2;KGF2

Function

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing.

Biological Context

Subcellular Location: Secreted
Disease Association: Aplasia of lacrimal and salivary glands (ALSG) : A rare condition characterized by dry conjunctival mucosae, irritable eyes, epiphora (constant tearing), and xerostomia (dryness of the mouth), which increases risk of dental erosion, dental caries, periodontal disease, and oral infections. ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular, and sublingual glands and absence of the lacrimal puncta. [The disease is caused by variants affecting the gene represented in this entry] | Lacrimo-auriculo-dento-digital syndrome 3 (LADD3) : A form of lacrimo-auriculo-dento-digital syndrome, an autosomal dominant disease characterized by aplastic/hypoplastic lacrimal and salivary glands and ducts, cup-shaped ears, hearing loss, hypodontia and enamel hypoplasia, and distal limb segments anomalies. In addition to these cardinal features, facial dysmorphism, malformations of the kidney and respiratory system and abnormal genitalia have been reported. Craniosynostosis and severe syndactyly are not observed. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Fibroblast growth factor 10 (FGF10) (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 38-208aa, with Tag free tag, molecular weight 19.3 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing

Subcellular Location

Secreted

Disease Association

Aplasia of lacrimal and salivary glands (ALSG) : A rare condition characterized by dry conjunctival mucosae, irritable eyes, epiphora (constant tearing), and xerostomia (dryness of the mouth), which increases risk of dental erosion, dental caries, periodontal disease, and oral infections. ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular, and sublingual glands and absence of the lacrimal puncta. [The disease is caused by variants affecting the gene represented in this entry] | Lacrimo-auriculo-dento-digital syndrome 3 (LADD3) : A form of lacrimo-auriculo-dento-digital syndrome, an autosomal dominant disease characterized by aplastic/hypoplastic lacrimal and salivary glands and ducts, cup-shaped ears, hearing loss, hypodontia and enamel hypoplasia, and distal limb segments anomalies. In addition to these cardinal features, facial dysmorphism, malformations of the kidney and respiratory system and abnormal genitalia have been reported. Craniosynostosis and severe syndactyly are not observed. [The disease is caused by variants affecting the gene represented in this entry]

Subunit

Interacts with FGFR1 and FGFR2. Interacts with FGFBP1

Gene: FGF10  |  Organism: Homo sapiens  |  Synonyms: Keratinocyte growth factor 2

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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