Recombinant Human Procathepsin L (CTSL) (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 37.2 kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Procathepsin L (CTSL) (Active)

Recombinant Human Procathepsin L (CTSL) (Active) — Functions in the regulation of cell cycle progression through proteolytic processing of the CUX1 transcription factor. Purity >90%.

SKU: BCACP-000455 Category:
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Product SKUBCACP-000455
Product DescriptionRecombinant Human Procathepsin L (CTSL) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 18-333aa. [Accession | P07711].
Uniprot No.P07711
Gene NamesCTSL
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region18-333aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight37.2 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Human MICA at 2 μg/mL can bind Anti-MICA/B recombinant antibody . The EC50 is 0.9163-1.108 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesProcathepsin L; EC:3.4.22.15; Cathepsin L1; Major excreted protein (MEP); CTSL; CTSL1

Function

Functions in the regulation of cell cycle progression through proteolytic processing of the CUX1 transcription factor. Translation initiation at downstream start sites allows the synthesis of isoforms that are devoid of a signal peptide and localize to the nucleus where they cleave the CUX1 transcription factor and modify its DNA binding properties.

Product Specifications

Recombinant Human Procathepsin L (CTSL) (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 18-333aa, with C-terminal 10xHis-tagged tag, molecular weight 37.2 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Human MICA at 2 μg/mL can bind Anti-MICA/B recombinant antibody . The EC50 is 0.9163-1.108 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Functions in the regulation of cell cycle progression through proteolytic processing of the CUX1 transcription factor (PubMed:15099520). Translation initiation at downstream start sites allows the synthesis of isoforms that are devoid of a signal peptide and localize to the nucleus where they cleave the CUX1 transcription factor and modify its DNA binding properties (PubMed:15099520)

Gene: CTSL  |  Organism: Homo sapiens

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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