Recombinant Human Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 6xHis-tagged, 21.78 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C), partial (Active)

Recombinant Human Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C), partial (Active) — Acts as a receptor for the cytotoxic ligand TRAIL but does not contain the intracellular death domain required to initiate apoptosis. Purity >95%.

SKU: BCACP-001248 Categories: ,
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Product SKUBCACP-001248
Product DescriptionRecombinant Human Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C) protein is expressed from Mammalian cell with C-terminal 6xHis-tagged. It contains 26-221aa. [Accession | O14798].
Uniprot No.O14798
Gene NamesTNFRSF10C
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region26-221aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight21.78 kDa
ActivityThe ED50 as determined in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D is 2-8 pg/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesTNFRSF10C; DCR1; LIT; TRAILR3; TRID; UNQ321/PRO366; Tumor necrosis factor receptor superfamily member 10C; Antagonist decoy receptor for TRAIL/Apo-2L; Decoy TRAIL receptor without death domain; Decoy receptor 1; DcR1; Lymphocyte inhibitor of TRAIL; TNF-related apoptosis-inducing ligand receptor 3; TRAIL receptor 3; TRAIL-R3; TRAIL receptor without an intracellular domain; CD antigen CD263

Function

Acts as a receptor for the cytotoxic ligand TRAIL but does not contain the intracellular death domain required to initiate apoptosis. By competing with the functional TRAIL receptors TNFRSF10A and TNFRSF10B for ligand binding, it functions as a decoy receptor that protects cells from TRAIL-induced apoptosis.

Product Specifications

Recombinant Human Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 26-221aa, with C-terminal 6xHis-tagged tag, molecular weight 21.78 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: The ED50 as determined in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D is 2-8 pg/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Acts as a receptor for the cytotoxic ligand TRAIL but does not contain the intracellular death domain required to initiate apoptosis. By competing with the functional TRAIL receptors TNFRSF10A and TNFRSF10B for ligand binding, it functions as a decoy receptor that protects cells from TRAIL-induced apoptosis

Gene: TNFRSF10C  |  Organism: Homo sapiens

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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